Job Opportunities

The McGraw Laboratory at Weill Cornell Medicine in New York City is seeking :

  • Two highly motivated postdoctoral fellows

Postdoctoral Associate Positions (2) in Receptor trafficking and Biochemistry

The McGraw Lab is looking for two postdocs in Cell Biology and Biochemistry in the Biochemistry Department at Weill Cornell Medical College, New York City.

As part of the McGraw Lab, the successful candidates will have the opportunity to work collaboratively with other postdocs, grad students, and research technicians within the lab under the supervision of Dr. Timothy E. McGraw. Weill Cornell Medical College is an equal opportunity, affirmative action educator and employer. Individuals from all genders and backgrounds are encouraged to apply.

Two projects are available for the candidates:

· Studies of insulin control of adipose biology

Some of the main objectives of our work are to characterize the Glut4 trafficking pathway in the presence and absence of insulin, to identify how the insulin-signal transduction regulates the movement of Glut4 vesicles, and to understand how other hormones control the tone of insulin response.

(Picatoste B. et al, 2021 - Brumfield A. et al, 2021, Vazirani RP. et al, 2016)

· Studies of the tumor microenvironment in lung cancer

Current work focuses on characterizing PD-L1 intracellular trafficking kinetics, any changes associated with oncogene signaling as well as PD-L1-intrinsic mutations. We want to identify the molecular players involved in regulation of PD-L1 recycling to the plasma membrane as well as functional assays tying the identified perturbations of PD-L1 trafficking to its immune inhibitory function.

(Altorki N et al, 2021, Letian A. et al, BioRxiv, 2021, Altorki N. et al, 2018)

More information about the McGraw Lab is available at www.mcgrawlab.org

Responsibilities:

· Work closely with other members of the McGraw Lab

· Perform cell-based experiments (cell culture, lentivirus infection, molecular biology)

· Technical skills include, but not limited, to quantitative immunofluorescence, Western Blot, RT-PCR, CRISPR-Cas9 gene editing, mouse model experiments

· Present projects to scientific audiences

· Prepare manuscripts for publication

Qualifications:

· Recent PhD, in Cell Biology, Molecular Biology, Biochemistry, or related backgrounds

· Experience with cell-based experiments

· Demonstrated ability to perform research independently and within a team

· Strong oral and written communication skills

· Excellent quantitative skills are required

· Experience with data analysis using Excel, GraphPad Prism, ImageJ and MetaMorph preferred

· Experience in mouse physiology is preferred

Please send, as a single pdf file, a CV and a brief narrative of your prior research experience to: temcgraw@med.cornell.edu


Salary Range is: $58,500 - $66,538

Weill Cornell Medicine provides the above salary range in compliance with the New York City law on Salary Transparency in Job Advertisements. The salary range listed is for full‐time employment not including bonuses, clinical incentive compensation, or benefits. Actual salaries depend on a variety of factors including but not limited to internal equity, specialty, training, and hospital/community needs.

The above salary range for New York City based roles represents WCM’s good faith and reasonable estimate of possible compensation at the time of posting.

Weill Cornell Medicine is an Equal Employment Opportunity Employer. Weill Cornell Medicine provides equal employment opportunities to all qualified applicants without regard to race, sex, sexual orientation, gender identity, national origin, color, age, religion, protected veteran or disability status, or genetic information


  • One research technician

Under supervision, the research technician assists scientists with laboratory and investigative procedures

This role performs various assays, imaging experiments, and other technical duties to assist with the research activities of the laboratory and may be required to work with animal models and/or human subjects

Responsibilities:

· Prepares and maintains detailed records, logs and summary reports of all procedures and results including graphs, scientific calculations, and statistical analysis charting.

· May be responsible for tissue & cell culture activities.

· May be responsible for animal husbandry, genotyping, surgeries, post-operative care, behavioral testing, sectioning and histology.

· May perform routine molecular biology laboratory procedures, such as PCR, protein and DNA electrophoresis, cloning and DNA preparation.

· May run routine biochemistry assays including western blotting and RT-PCR.

· May perform microscopic imaging analyses.

· May be responsible for the receipt, storage, cataloguing and shipment of samples within and between institutions.

· Ensures a clean working area and is responsible for washing and storing glassware.

· Ensures the safe laboratory practices are followed, including the use and disposal of chemicals and hazardous materials.

· Analyzes data using computer software and reports results to the principle investigator(s).

· Provides technical support to faculty and staff including training of new employees, residents, postdoctoral associates, fellows and students.

· Participates in planning and carrying out experiments. Assists in preparing research protocols.

· Conducts library research and literature searches using various computer systems. Assists in editing scientific publications, abstracts and posters.

· Maintains inventory of supplies, equipment and/or reagents. May order supplies/equipment/reagents as authorized or ensure that needs are escalated appropriately. Receives supply orders and confirms accuracy of delivery. May assist with cost control.

· Ensures that facilities and equipment are in optimal and proper working condition. Coordinates preventative maintenance and repairs as needed. May perform minor repairs if qualified and as needed. May advise on upgrades for performance enhancements.

Education

· Bachelor's Degree in related field

Experience

· Some bench lab related experience. Minimum two-year commitment due to a substantial training effort associated with the position

Knowledge, Skills and Abilities

· Demonstrated organizational skills and ability to pay close attention to detail.

· Ability to plan and prioritize work while responding flexibly to rapidly changing priorities.

Licenses and Certifications

Working Conditions/Physical Demands

· Standard laboratory conditions.

· Ability to work flexible hours.

· This position may handle radioactive material and/or biologic materials from human subjects as required.

· This position may require standing or sitting for long periods of time.

· This role may require working within Biologic Safety Level 1, 2 and/or 3 facilities


Please send, as a single pdf file, a resume and a brief narrative of your prior research experience to: jew2019@med.cornell.edu

Salary Range is: $40,092 - $51,700

Weill Cornell Medicine provides the above salary range in compliance with the New York City law on Salary Transparency in Job Advertisements. The salary range listed is for full‐time employment not including bonuses, clinical incentive compensation, or benefits. Actual salaries depend on a variety of factors including but not limited to internal equity, specialty, training, and hospital/community needs.

The above salary range for New York City based roles represents WCM’s good faith and reasonable estimate of possible compensation at the time of posting.

Weill Cornell Medicine is an Equal Employment Opportunity Employer. Weill Cornell Medicine provides equal employment opportunities to all qualified applicants without regard to race, sex, sexual orientation, gender identity, national origin, color, age, religion, protected veteran or disability status, or genetic information

Graduate students

Prospective graduate students should apply through the Weill Cornell Graduate School

Current graduate students interested in rotating should email Dr. McGraw at temcgraw@med.cornell.edu

Weill Cornell Medicine is a comprehensive academic medical center that's committed to excellence in patient care, scientific discovery, and the education of future physicians in New York City and around the world. Our doctors and scientists-faculty from Weill Cornell Medical College, Weill Cornell Graduate School of Medical Sciences, and the Weill Cornell Physician Organization-are engaged in world-class clinical care and cuttingedge research that connect patients to the latest treatment innovations and prevention strategies. Located in the heart of the Upper East Side's scientific corridor, Weill Cornell Medicine's powerful network of collaborators extends to its parent university Cornell University; to Qatar, where an international campus offers a U.S. medical degree; and to programs in Tanzania, Haiti, Brazil, Austria and Turkey. Our medical practices serve communities throughout New York City, and our faculty provide comprehensive care at NewYork-Presbyterian Hospital/Weill Cornell Medical Center, NewYork-Presbyterian/Lower Manhattan Hospital, and NewYork-Presbyterian/Queens. At Weill Cornell Medicine, we work together to treat each individual, not just their conditions or illnesses, as we strive to deliver the finest possible care for our patients - the center of everything we do. Weill Cornell Medicine is an Equal Employment Opportunity/Minorities/Females/Vet/Disabled employer.